Ebastine-d6

Product Description: Ebastine-d6 is deuterated labeled Ebastine (HY-B0674). Ebastine (LAS-W 090) is an orally active, second-generation histamine H1 receptor antagonist. Ebastine can be used for the symptoms of allergic rhinitis and chronic idiopathic urticaria research[1].

Applications: Metabolism-protein/nucleotide metabolism

Formula: C32H33D6NO2

References: [1]Fu-Ming Tsai, et al. Extracellular Signal-Regulated Kinase Mediates Ebastine-Induced Human Follicle Dermal Papilla Cell Proliferation. Biomed Res Int. 2019 Feb 11;2019:6360503./[2]J Sastre. Ebastine in allergic rhinitis and chronic idiopathic urticarial. Allergy. 2008 Dec;63 Suppl 89:1-20./[3]Fujii, et al. Absorption, distribution, metabolism and excretion of [14C]ebastine after a single administration in rats. Arzneimittelforschung. 1994 Apr;44(4):527-38./[4]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

Molecular Weight: 475.69

Research Area: Endocrinology; Inflammation/Immunology

Solubility: 10 mM in DMSO

Target: Histamine Receptor;Isotope-Labeled Compounds

• Artikelnummer: MEXHY-B0674S1-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-B0674S1-0
• Verpackungseinheit: Get quote
• Mengeneinheit: STK