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eCF506-d5
eCF506-d5
Artikelnummer
MEXHY-112096S-0
Verpackungseinheit
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Hersteller
MedChemExpress
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Product Description: eCF506-d5 is deuterated labeled eCF506 (HY-112096). eCF506 is a highly potent and orally bioavailable inhibitor of the non-receptor tyrosine kinase Src with an IC50 of less than 0.5 nM.
Applications: Cancer-Kinase/protease
Formula: C26H33D5N8O3
References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216./[2]Fraser C, et al. Rapid Discovery and Structure-Activity Relationships of Pyrazolopyrimidines That Potently Suppress Breast Cancer Cell Growth via SRC Kinase Inhibition with Exceptional Selectivity over ABL Kinase. J Med Chem. 2016 May 26;59(10):4697-710.
Molecular Weight: 515.66
Research Area: Cancer
Solubility: 10 mM in DMSO
Target: Isotope-Labeled Compounds;Src
Applications: Cancer-Kinase/protease
Formula: C26H33D5N8O3
References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216./[2]Fraser C, et al. Rapid Discovery and Structure-Activity Relationships of Pyrazolopyrimidines That Potently Suppress Breast Cancer Cell Growth via SRC Kinase Inhibition with Exceptional Selectivity over ABL Kinase. J Med Chem. 2016 May 26;59(10):4697-710.
Molecular Weight: 515.66
Research Area: Cancer
Solubility: 10 mM in DMSO
Target: Isotope-Labeled Compounds;Src
| Artikelnummer | MEXHY-112096S-0 |
|---|---|
| Hersteller | MedChemExpress |
| Hersteller Artikelnummer | HY-112096S-0 |
| Green Labware | Nein |
| Verpackungseinheit | Get quote |
| Mengeneinheit | STK |
| Produktinformation (PDF) | Download |
| MSDS (PDF) |
|
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Dr. Andreas Bergmann
