(±)-Epicatechin-13C3, CAS 1217780-28-3

Product Description: (±)-Epicatechin-13C3 is the 13C labeled (±)-Epicatechin. (-)-Epicatechin (HY-N0001) inhibits cyclooxygenase-1 (COX-1) with an IC50 of 3.2 μM. (-)-Epicatechin inhibits the IL-1β-induced expression of iNOS by blocking the nuclear localization of the p65 subunit of NF-κB[1].

Formula: C12 13C3H14O6

References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216./[2]Waffo-Téguo P, et al. Potential cancer-chemopreventive activities of wine stilbenoids and flavans extracted from grape (Vitis vinifera) cell cultures. Nutr Cancer. 2001;40(2):173-9./[3]Shay J, et al. Molecular Mechanisms and Therapeutic Effects of (-)-Epicatechin and Other Polyphenols in Cancer, Inflammation, Diabetes, and Neurodegeneration. Oxid Med Cell Longev. 2015;2015:181260./[4]Nogueira L, et al. (-)-Epicatechin enhances fatigue resistance and oxidative capacity in mouse muscle. J Physiol. 2011 Sep 15;589(Pt 18):4615-31.

CAS Number: 1217780-28-3

Molecular Weight: 293.25

Research Area: Cancer; Inflammation/Immunology

Solubility: 10 mM in DMSO

Target: COX;Endogenous Metabolite;Ferroptosis;Isotope-Labeled Compounds

• Artikelnummer: MEXHY-N0001S-5
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-N0001S-5
• Green Labware: Nein
• Verpackungseinheit: 5mg
• Mengeneinheit: STK