Eprosartan-d6

Product Description: Eprosartan-d6 is deuterated labeled Eprosartan (HY-117743). Eprosartan (SKF-108566J free base) is a selective, competitive, nonpeptid and orally active angiotensin II receptor antagonist, used as an antihypertensive. Eprosartan binds angiotensin II receptor with IC50s of 9.2 nM and 3.9 nM in rat and human adrenal cortical membranes, respectively [1].

Applications: Neuroscience-Neuromodulation

Formula: C23H18D6N2O4S

References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216./[2]R M Edwards, et al. Pharmacological characterization of the nonpeptide angiotensin II receptor antagonist, SK&F 108566. J Pharmacol Exp Ther. 1992 Jan;260(1):175-81.

Molecular Weight: 430.55

Research Area: Cardiovascular Disease

Solubility: 10 mM in DMSO

Target: Angiotensin Receptor;Isotope-Labeled Compounds

• Artikelnummer: MEXHY-117743S1-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-117743S1-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK