Product Description: Fumonisin B1-13C34 is the 13C labeled Fumonisin B1 (HY-N6719)[1]. Fumonisin B1 is a mycotoxin produced from Fusarium moniliforme. Fumonisin B1 is a potent inhibitor of sphingosine N-acyltransferase (ceramide synthase) and disrupts de novo sphingolipid biosynthesis. Fumonisin B1 is the most abundant and toxic fumonisin[2][3].
Applications: COVID-19-immunoregulation
Formula: 13C34H59NO15
References: [1]Henry MH, et al. The toxicity of fumonisin B1, B2, and B3, individually and in combination, in chicken embryos. Poult Sci. 2001 Apr;80(4):401-7./[2]Wang SK, et al. Effect of fumonisin B₁ on the cell cycle of normal human liver cells. Mol Med Rep. 2013 Jun;7(6):1970-6./[3]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-220.
CAS Number: 1217458-62-2
Molecular Weight: 755.58
Research Area: Infection
Solubility: 10 mM in DMSO
Target: Isotope-Labeled Compounds