Product Description: Fumonisin B2-13C34 is the 13C labeled Fumonisin B2 (HY-N6723)[1]. Fumonisin B2, a mycotoxin produced by Fusarium moniliforme in various grains, is a potent inhibitor of sphingosine N-acyltransferase (ceramide synthase) and disrupts de novo sphingolipid biosynthesis[2][3].
Applications: COVID-19-immunoregulation
Formula: 13C34H59NO14
References: [1]Henry MH, et al. The toxicity of fumonisin B1, B2, and B3, individually and in combination, in chicken embryos. Poult Sci. 2001 Apr;80(4):401-7./[2]Wei T, et al. Natural occurrence of fumonisins B1 and B2 in corn in four provinces of China. Food Addit Contam Part B Surveill. 2013;6(4):270-4./[3]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-220.
CAS Number: 1217481-36-1
Molecular Weight: 739.58
Research Area: Infection
Solubility: 10 mM in DMSO
Target: Isotope-Labeled Compounds