Glycoursodeoxycholic Acid-d4, CAS 2044276-17-5

Product Description: Glycoursodeoxycholic acid-d4 (Ursodeoxycholylglycine-d4) is the deuterium labeled Glycoursodeoxycholic acid. Glycoursodeoxycholic acid, a acyl glycine and a bile acid-glycine conjugate, is a metabolite of ursodeoxycholic acid[1][2].

Applications: Neuroscience-Neuromodulation

Formula: C26H39D4NO5

References: [1]Vaz AR, et al. Bilirubin selectively inhibits cytochrome c oxidase activity and induces apoptosis in immature cortical neurons: assessment of the protective effects of glycoursodeoxycholic acid. J Neurochem. 2010 Jan;112(1):56-65./[2]Vaz AR, et al. Glycoursodeoxycholic acid reduces matrix metalloproteinase-9 and caspase-9 activation in a cellular model of superoxide dismutase-1 neurodegeneration./[3]Palmela I, et al. Hydrophilic bile acids protect human blood-brain barrier endothelial cells from disruption by unconjugated bilirubin: an in vitro study. Front Neurosci. 2015 Mar 13;9:80./[4]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

CAS Number: 2044276-17-5

Molecular Weight: 453.65

Compound Purity: 98.88

Research Area: Neurological Disease

Solubility: DMSO : 50 mg/mL (ultrasonic)

Target: Endogenous Metabolite;Isotope-Labeled Compounds

• Artikelnummer: MEXHY-N1424S-1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-N1424S-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK