Hydrocortisone-d7

Product Description: Hydrocortisone-d7 is the deuterium labeled Hydrocortisone. Hydrocortisone (Cortisol) is a steroid hormone or glucocorticoid secreted by the adrenal cortex[1].

Formula: C21H23D7O5

References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. /[2]Förster C, et al. Differential effects of hydrocortisone and TNFalpha on tight junction proteins in an in vitro model of the human blood-brain barrier. J Physiol. 2008 Apr 1;586(7):1937-49./[3]Bellinghausen I, et al. Inhibition of human allergic T-cell responses by IL-10-treated dendritic cells: differences from hydrocortisone-treated dendritic cells. J Allergy Clin Immunol. 2001 Aug;108(2):242-9./[4]Chappell D, et al. Hydrocortisone preserves the vascular barrier by protecting the endothelial glycocalyx. Anesthesiology. 2007 Nov;107(5):776-84.

Molecular Weight: 369.50

Research Area: Inflammation/Immunology; Endocrinology; Cancer

Solubility: 10 mM in DMSO

Target: Endogenous Metabolite;Glucocorticoid Receptor;Isotope-Labeled Compounds

• Artikelnummer: MEXHY-N0583S1-2500UG
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-N0583S1-2500UG
• Green Labware: Nein
• Verpackungseinheit: 2500 ug
• Mengeneinheit: STK