Hydroxyzine-d4' (dihydrochloride), CAS 1219805-91-0

Product Description: Hydroxyzine-d4 (dihydrochloride) is the deuterium labeled Hydroxyzine dihydrochloride. Hydroxyzine dihydrochloride, a benzodiazepine antihistamine agent, acts as a orally active histamine H1-receptor and serotonin antagonist. Hydroxyzine dihydrochloride has anxiolytic effect and can be used forthe research of generalised anxiety disorder[1][2].

Formula: C21H25D4Cl3N2O2

References: [1]Nikita Shekhar Sawantdesai, et al. Evaluation of anxiolytic effects of aripiprazole and hydroxyzine as a combination in mice. J Basic Clin Pharm. 2016 Sep;7(4):97-104./[2]Minogiannis, P., et al., Hydroxyzine inhibits neurogenic bladder mast cell activation. Int J Immunopharmacol, 1998. 20(10): p. 553-63./[3]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

CAS Number: 1219805-91-0

Molecular Weight: 451.85

Compound Purity: 98.0

Research Area: Inflammation/Immunology; Endocrinology

Solubility: 10 mM in DMSO

Target: Histamine Receptor

• Artikelnummer: MEXHY-B0548AS1-1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-B0548AS1-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK