Indapamide-d6

Product Description: Indapamide-d6 is a deuterated labeled Indapamide[1]. Indapamide is an orally active sulphonamide diuretic agent, that can reduce blood pressure by decreasing vascular reactivity and peripheral vascular resistance. Indapamide is also can reduce left ventricular hypertrophy[2][5].

Formula: C17H12D6ClN3O3S

References: [1]Chaffman, M, et, al. Indapamide. Drugs 28, 189–235 (1984)./[2]Furman BL, et, al. A further examination of the possible effects of indapamide on glucose tolerance and insulin secretion in the rat and mouse. J Pharm Pharmacol. 1981 Nov;33(11):735-7./[3]Lalande A, et, al. Indapamide, a thiazide-like diuretic, decreases bone resorption in vitro. J Bone Miner Res. 2001 Feb;16(2):361-70./[4]Ma F, et, al. Indapamide lowers blood pressure by increasing production of epoxyeicosatrienoic acids in the kidney. Mol Pharmacol. 2013 Aug;84(2):286-95./[5]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

Molecular Weight: 385.90

Research Area: Cardiovascular Disease

Target: Isotope-Labeled Compounds;Potassium Channel

• Artikelnummer: MEXHY-B0259S3-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-B0259S3-0
• Verpackungseinheit: Get quote
• Mengeneinheit: STK