Inosine-2,8-d2, CAS 697807-01-5

Product Description: Inosine-2,8-d2 is the deuterium labeled Inosine. Inosine is an endogenous purine nucleoside produced by catabolism of adenosine. Inosine has anti-inflammatory, antinociceptive, immunomodulatory and neuroprotective effects. Inosine is an agonist for adenosine A1 (A1R) and A2A (A2AR) receptors[1][2][3].

Applications: COVID-19-immunoregulation

Formula: C10H10D2N4O5

References: [1]Filipe Marques Gonçalves, et al. Signaling pathways underlying the antidepressant-like effect of inosine in mice. Purinergic Signal. 2017 Jun; 13(2): 203-214./[2]Ajith A. Welihinda, et al. The adenosine metabolite inosine is a functional agonist of the adenosine A2A receptor with a unique signaling bias. Cell Signal. 2016 Jun; 28(6): 552-560./[3]Francisney Pinto Nascimento, et al. Adenosine A1 receptor-dependent antinociception induced by inosine in mice: pharmacological, genetic and biochemical aspects. Mol Neurobiol. 2015;51(3):1368-78./[4]Sara Cipriani, et al. Protection by inosine in a cellular model of Parkinson’s disease. Neuroscience. 2014 Aug 22; 274: 242-249./[5]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

CAS Number: 697807-01-5

Molecular Weight: 270.24

Research Area: Inflammation/Immunology; Neurological Disease

Solubility: 10 mM in DMSO

Target: Adenosine Receptor;Endogenous Metabolite

• Artikelnummer: MEXHY-N0092S-5
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-N0092S-5
• Green Labware: Nein
• Verpackungseinheit: 5mg
• Mengeneinheit: STK