Isonicotinic acid-d4, CAS 53907-55-4

Product Description: Isonicotinic acid-d4 is the deuterium labeled Isonicotinic acid[1]. Isonicotinic acid is a metabolite of Isoniazid. Isoniazid is converted to Isonicotinic acid by hydrazinolysis, with the Isoniazid to Isonicotinic acid biotransformation also to be catalyzed by cytochrome P450 (CYP) enzymes, e.g., CYP2C[2].

Applications: Metabolism-protein/nucleotide metabolism

Formula: C6HD4NO2

References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216./[2]Seng KY, et al. Population pharmacokinetic analysis of isoniazid, acetylisoniazid, and isonicotinic acid in healthy volunteers. Antimicrob Agents Chemother. 2015 Nov;59(11):6791-9.

CAS Number: 53907-55-4

Molecular Weight: 127.13

Research Area: Others

Solubility: 10 mM in DMSO

Target: Drug Metabolite;Endogenous Metabolite

• Artikelnummer: MEXHY-I0736S-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-I0736S-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK