Isoxsuprine-d6 (hydrochloride), CAS 2706004-35-3

Product Description: Isoxsuprine-d6 (hydrochloride) is the deuterium labeled Isoxsuprine hydrochloride. Isoxsuprine hydrochloride is a beta-adrenergic receptor agonist with Kis of 13.65 μΜ and 3.48 μΜ for myometrial and placcntal beta-adrenergic receptor, respectively. Isoxsuprine hydrochloride is also a NMDA receptor antagonist.

Formula: C18H18D6ClNO3

References: [1]Falkay G, et al. Affinity of tocolytic agents on human placental and myometrial beta-adrenergic receptors. J Perinat Med. 1986;14(2):109-13./[2]Kretschy N, et al. In vitro inhibition of breast cancer spheroid-induced lymphendothelial defects resembling intravasation into the lymphatic vasculature by acetohexamide, isoxsuprine, nifedipin and proadifen. Br J Cancer. 2013 Feb 19;108(3):570-8./[3]Hill JW, et al. Identification of isoxsuprine hydrochloride as a neuroprotectant in ischemic stroke through cell-based high-throughput screening. PLoS One. 2014 May 7;9(5):e96761./[4]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

CAS Number: 2706004-35-3

Molecular Weight: 343.88

Compound Purity: 99.73

Research Area: Neurological Disease; Endocrinology

Solubility: 10 mM in DMSO

Target: Adrenergic Receptor;iGluR;Isotope-Labeled Compounds

• Artikelnummer: MEXHY-B1270S-1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-B1270S-1
• Green Labware: Nein
• Verpackungseinheit: 1mg
• Mengeneinheit: STK