L-DOPA-d6, CAS 713140-75-1

Product Description: L-DOPA-d6 is the deuterium labeled L-DOPA. L-DOPA (Levodopa) is an orally active metabolic precursor of neurotransmitters dopamine. L-DOPA can cross the blood-brain barrier and is converted into dopamine in the brain. L-DOPA has anti-allodynic effects and the potential for Parkinson's disease[1][2][3].

Formula: C9H5D6NO4

References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. /[2]Hyland K, et al. Aromatic L-amino acid decarboxylase deficiency: diagnostic methodology. Clin Chem. 1992 Dec;38(12):2405-10./[3]Merims D, et al. Dopamine dysregulation syndrome, addiction and behavioral changes in Parkinson's disease. Parkinsonism Relat Disord. 2008;14(4):273-80. Epub 2007 Nov 7./[4]Perez-Pardo P, et al. Additive Effects of Levodopa and a Neurorestorative Diet in a Mouse Model of Parkinson's Disease. Front Aging Neurosci. 2018 Aug 3;10:237./[5]Park HJ, et al. Anti-allodynic effects of levodopa in neuropathic rats. Yonsei Med J. 2013 Mar 1;54(2):330-5.

CAS Number: 713140-75-1

Molecular Weight: 203.22

Compound Purity: 99.0

Research Area: Neurological Disease

Solubility: 10 mM in DMSO

Target: Dopamine Receptor;Endogenous Metabolite

• Artikelnummer: MEXHY-N0304S-1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-N0304S-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK