Product Description: L-Histidine-13C6,15N3 is 13C and 15N-labeled L-Histidine (HY-N0832). L-Histidine is an essential amino acid for infants. L-Histidine is an inhibitor of mitochondrial glutamine transport.
Applications: Metabolism-sugar/lipid metabolism
Formula: 13C6H9 15N3O2
References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216./[2]Bou Zeidan M, et al. L-histidine inhibits biofilm formation and FLO11-associated phenotypes in Saccharomyces cerevisiae flor yeasts. PLoS One. 2014 Nov 4;9(11):e112141./[3]Rama Rao KV, et al. Brain edema in acute liver failure: inhibition by L-histidine. Am J Pathol. 2010 Mar;176(3):1400-8./[4]Yoshikawa T, et al. Insufficient intake of L-histidine reduces brain histamine and causes anxiety-like behaviors in male mice. J Nutr. 2014 Oct;144(10):1637-41.
CAS Number: 741656-40-6
Molecular Weight: 164.09
Research Area: Metabolic Disease; Inflammation/Immunology; Neurological Disease
Solubility: 10 mM in DMSO
Target: Endogenous Metabolite;Isotope-Labeled Compounds;Mitochondrial Metabolism