Lamotrigine-13C2,15N2,d3

Product Description: Lamotrigine-13C2,15N2,d3 is 15N and deuterated labeled Lamotrigine (HY-B0495). Lamotrigine (BW430C) is a potent and orally active anticonvulsant or antiepileptic agent. Lamotrigine selectively blocks voltage-gated Na+ channels, stabilizing presynaptic neuronal membranes and inhibiting glutamate release. Lamotrigine can be used for the research of epilepsy,?focal seizure, et al[1][2].

Applications: Cancer-programmed cell death

Formula: C7 13C2H5D3Cl2N3 15N2

References: [1]M J Leach, et al. Pharmacological studies on lamotrigine, a novel potential antiepileptic drug: II. Neurochemical studies on the mechanism of action. Epilepsia. Sep-Oct 1986;27(5):490-7./[2]Damianka P Getova, et al. A study of the effects of lamotrigine on mice using two convulsive tests. Folia Med (Plovdiv). Apr-Jun 2011;53(2):57-62./[3]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

Molecular Weight: 264.09

Research Area: Cancer; Neurological Disease

Solubility: 10 mM in DMSO

Target: Autophagy;Isotope-Labeled Compounds;Sodium Channel

• Artikelnummer: MEXHY-B0495S6-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-B0495S6-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK