Lansoprazole sulfone-d4, CAS 1184999-77-6

Product Description: Lansoprazole sulfone-d4 (AG-1813-d4) is the deuterium labeled Lansoprazole sulfone. Lansoprazole sulfone-d4 is an orally active and selective inhibitor of H+, K+-ATPase. Lansoprazole sulfone-d4 can significantly stimulates gastric acid secretion by inhibiting H+, K+-ATPase. Lansoprazole sulfone-d4 has potential applications in duodenal ulcer, gastric ulcer, gastroesophageal reflux disease and Zolinger Ellison disease[1][2][3].

Formula: C16H10D4F3N3O3S

References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216./[2]Swamy G, et al. Crystal structure of lansoprazole sulfone[J]. Journal of Structural Chemistry, 2007, 48: 715-718./[3]Karol MD, et al. Lansoprazole pharmacokinetics in subjects with various degrees of kidney function. Clin Pharmacol Ther. 1997 Apr;61(4):450-8.

CAS Number: 1184999-77-6

Molecular Weight: 389.39

Research Area: Others

Solubility: 10 mM in DMSO

Target: Isotope-Labeled Compounds;Proton Pump

• Artikelnummer: MEXHY-W008614S-5
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-W008614S-5
• Green Labware: Nein
• Verpackungseinheit: 5mg
• Mengeneinheit: STK