Leniolisib-d5

Product Description: Leniolisib-d5 is a deuterated labeled Leniolisib[1]. Leniolisib (CDZ173) is a potent and selective PI3Kδ inhibitor. Leniolisib has the potential for immunodeficiency disorders treatment.

Formula: C21H20D5F3N6O2

References: [1]Hoegenauer K, et al. Discovery of CDZ173 (Leniolisib), Representing a Structurally Novel Class of PI3K Delta-Selective Inhibitors. ACS Med Chem Lett. 2017 Aug 25;8(9):975-980. /[2]Rao V, et al. Effective 'Activated PI3Kd Syndrome' -targeted therapy with PI3Kd inhibitor leniolisib. The New England journal of medicine: NEJM. ISSN 0028-4793; 1533-4406/[3]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

Molecular Weight: 455.49

Compound Purity: 98.78

Research Area: Inflammation/Immunology

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: Isotope-Labeled Compounds;PI3K

• Artikelnummer: MEXHY-17635S-10
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-17635S-10
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK