Product Description: Linifanib-d4 (ABT-869-d4; AL-39324-d4) is deuterium-labeled Linifanib (HY-50751)[1].
Applications: Cancer-Kinase/protease
Formula: C21H14D4FN5O
References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216./[2]Smith K A, et al. Soil and environmental analysis[M]. Marcel Dekker Incorporated, 2000./[3]Fan T W M, et al. Stable isotope-resolved metabolomics and applications for drug development[J]. Pharmacology & therapeutics, 2012, 133(3): 366-391.
Molecular Weight: 379.42
Research Area: Cancer
Target: Apoptosis;Autophagy;c-Fms;c-Kit;FLT3;Isotope-Labeled Compounds;PDGFR;VEGFR