Lofexidine-d4 (hydrochloride), CAS 1206845-57-9

Product Description: Lofexidine-d4 (hydrochloride) (Baq-168-d4) is the deuterium labeled Lofexidine hydrochloride. Lofexidine hydrochloride is a selective α2-receptor agonist, commonly used to alleviate the physical symptoms of heroin and other types of opioid withdrawal[1][2].

Applications: Metabolism-protein/nucleotide metabolism

Formula: C11H9D4Cl3N2O

References: [1]Vartak AP, et al. The preclinical discovery of lofexidine for the treatment of opiate addiction. Expert Opin Drug Discov. 2014 Nov;9(11):1371-7./[2]Gish EC, et al. Lofexidine, an {alpha}2-receptor agonist for opioid detoxification. Ann Pharmacother. 2010 Feb;44(2):343-51./[3]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

CAS Number: 1206845-57-9

Molecular Weight: 299.62

Research Area: Neurological Disease; Endocrinology

Solubility: 10 mM in DMSO

Target: Adrenergic Receptor

• Artikelnummer: MEXHY-B1052S-1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-B1052S-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK