Moxonidine-13C,d3 (hydrochloride)

Moxonidine-13C,d3 (hydrochloride)
Artikelnummer
MEXHY-B0374AS-0
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MedChemExpress

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Product Description: Moxonidine-13C,d3 hydrochloride is 13C and deuterated labeled Moxonidine hydrochloride (HY-B0374A). Moxonidine (BDF5895) hydrochloride is an imidazoline type 1 receptor (I1-R) selective agonist and antihypertensive agent.

Applications: Neuroscience-Neuromodulation

Formula: C8 13CH10D3Cl2N5O

References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216./[2]Schafer, U., et al., Presynaptic effects of moxonidine in isolated buffer perfused rat hearts: role of imidazoline-1 receptors and alpha2-adrenoceptors. J Pharmacol Exp Ther, 2002. 303(3): p. 1163-70./[3]Chan, C.K., et al., Imidazoline receptors associated with noradrenergic terminals in the rostral ventrolateral medulla mediate the hypotensive responses of moxonidine but not clonidine. Neuroscience, 2005. 132(4): p. 991-1007.

Molecular Weight: 282.15

Research Area: Neurological Disease

Solubility: 10 mM in DMSO

Target: Imidazoline Receptor;Isotope-Labeled Compounds
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Artikelnummer MEXHY-B0374AS-0
Hersteller MedChemExpress
Hersteller Artikelnummer HY-B0374AS-0
Green Labware Nein
Verpackungseinheit Get quote
Mengeneinheit STK
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