Moxonidine-d7

Product Description: Moxonidine-d7 is deuterated labeled Moxonidine (HY-B0374). Moxonidine (BDF5895) is an imidazoline type 1 receptor (I1-R) selective agonist and antihypertensive agent.

Applications: Neuroscience-Neuromodulation

Formula: C9H5D7ClN5O

References: [1]Schafer, U., et al., Presynaptic effects of moxonidine in isolated buffer perfused rat hearts: role of imidazoline-1 receptors and alpha2-adrenoceptors. J Pharmacol Exp Ther, 2002. 303(3): p. 1163-70./[2]Chan, C.K., et al., Imidazoline receptors associated with noradrenergic terminals in the rostral ventrolateral medulla mediate the hypotensive responses of moxonidine but not clonidine. Neuroscience, 2005. 132(4): p. 991-1007./[3]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

Molecular Weight: 248.72

Research Area: Neurological Disease

Solubility: 10 mM in DMSO

Target: Imidazoline Receptor;Isotope-Labeled Compounds

• Artikelnummer: MEXHY-B0374S1-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-B0374S1-0
• Verpackungseinheit: Get quote
• Mengeneinheit: STK