Mycophenolate Mofetil-d4 (hydrochloride)

Product Description: Mycophenolate Mofetil-d4 hydrochloride is deuterated labeled Mycophenolate mofetil hydrochloride (HY-B0199A). Mycophenolate mofetil (RS 61443) hydrochloride is a immunosuppressant, a non-competitive, selective and reversible inhibitor of inosine monophosphate dehydrogenase (IMPD) type I/II with IC50s of 39 nM and 27 nM, respectively.

Applications: Cancer-programmed cell death

Formula: C23H28D4ClNO7

References: [1]Nakanishi, T., et al., Effect of the inosine 5'-monophosphate dehydrogenase inhibitor BMS-566419 on rat cardiac allograft rejection. Int Immunopharmacol, 2010. 10(1): p. 91-7./[2]Dehghani, F., et al., Inhibition of microglial and astrocytic inflammatory responses by the immunosuppressant mycophenolate mofetil. Neuropathol Appl Neurobiol, 2010. 36(7): p. 598-611./[3]Ozgen, M., et al., Mycophenolate mofetil and daclizumab targeting T lymphocytes in bleomycin-induced experimental scleroderma. Clin Exp Dermatol, 2012. 37(1): p. 48-54./[4]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

Molecular Weight: 473.98

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Bacterial;Endogenous Metabolite;Isotope-Labeled Compounds

• Artikelnummer: MEXHY-B0199AS-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-B0199AS-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK