Product Description: Myosmine-d4 is the deuterium labeled Myosmine. Myosmine, a specific tobacco alkaloid in nuts and nut products, has low affinity for a4b2 nicotinic acetylcholinergic receptors (nAChR) with a Ki of 3300 nM[1][2].
Formula: C9H6D4N2
References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. /[2]G Ferretti, er al. Binding of Nicotine and Homoazanicotine Analogues at Neuronal Nicotinic Acetylcholinergic (nACh) Receptors. Bioorg Med Chem Lett. 2003 Feb 24;13(4):733-5./[3]Wolfgang Zwickenpflug, et al. Metabolism of Myosmine in Wistar Rats. Drug Metab Dispos. 2005 Nov;33(11):1648-56.
CAS Number: 66148-17-2
Molecular Weight: 150.21
Compound Purity: 98.0
Research Area: Metabolic Disease
Solubility: 10 mM in DMSO
Target: nAChR