Nerolidol-d4

Product Description: Nerolidol-d4 is deuterated labeled Tenuazonic acid (HY-N6715). Tenuazonic acid, belonging to tetramic acids that are the largest family of natural products, is a putative nonhost-selective mycotoxin isolated from Alternaria alternate[1]. Tenuazonic acid blocks electron transport beyond primary quinone acceptor (QA) by interacting with D1 protein and it is a broad-spectrum and effective photosystem II (PSII) inhibitor[2].

Applications: Cancer-programmed cell death

Formula: C15H22D4O

References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216./[2]Nogueira Neto JD, et al. Antioxidant effects of nerolidol in mice hippocampus after open field test. Neurochem Res. 2013 Sep;38(9):1861-70./[3]Chan WK, et al. Nerolidol: A Sesquiterpene Alcohol with Multi-Faceted Pharmacological and Biological Activities. Molecules. 2016 Apr 28;21(5):529./[4]Nerolidol, et al. In vitro antileishmanial and cytotoxic activities of nerolidol are associated with changes in plasma membrane dynamics. Biochim Biophys Acta Biomembr. 2019 Jun 1;1861(6):1049-1056.

Molecular Weight: 226.39

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Bacterial;Endogenous Metabolite;Fungal;Isotope-Labeled Compounds;Parasite

• Artikelnummer: MEXHY-N1944S-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-N1944S-0
• Verpackungseinheit: Get quote
• Mengeneinheit: STK