Nivalenol-13C15, CAS 911392-40-0

Product Description: Nivalenol-13C15 is the 13C labeled Nivalenol (HY-N6801)[1]. Nivalenol, classified as type B trichotecenes toxins produced by Fusarium graminearum, is a fungal metabolite present in agricultural product[2]. Nivalenol induces cell death through caspase-dependent mechanisms and via the intrinsic apoptotic pathway. Nivalenol affects the immune system, causes emesis, growth retardation, reproductive disorders and has a haematotoxic/myelotoxic effect[3].

Applications: COVID-19-immunoregulation

Formula: 13C15H20O7

References: [1]Bryła M, et al. Natural Occurrence of Nivalenol, Deoxynivalenol, and Deoxynivalenol-3-Glucoside in Polish Winter Wheat. Toxins (Basel). 2018 Feb 13;10(2)./[2]Aupanun S, et al. Individual and combined mycotoxins deoxynivalenol, nivalenol, and fusarenon-X induced apoptosis in lymphoid tissues of mice after oral exposure. Toxicon. 2019 Jul;165:83-94./[3]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-220.

CAS Number: 911392-40-0

Molecular Weight: 327.20

Research Area: Infection

Solubility: 10 mM in DMSO

Target: Isotope-Labeled Compounds

• Artikelnummer: MEXHY-N6801S-30UG
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-N6801S-30UG
• Verpackungseinheit: 30 ug(76.40 μM * 1.2 mL in Acetonitrile)
• Mengeneinheit: STK