Odevixibat-13C6

Product Description: Odevixibat-13C6 is 13C labeled Odevixibat (HY-109120). Odevixibat (A4250) is a selective and orally active ileal apical sodium-dependent bile acid transporter (ASBT) inhibitor. Odevixibat decreases cholestatic liver and bile duct injury in mice model. Odevixibat has the potential for the treatment of primary biliary cirrhosis[1].

Applications: Metabolism-protein/nucleotide metabolism

Formula: C31 13C6H48N4O8S2

References: [1]Baghdasaryan A, et al. Inhibition of intestinal bile acid absorption improves cholestatic liver and bile duct injury in a mouse model of sclerosing cholangitis.J Hepatol. 2016 Mar;64(3):674-81./[2]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

Molecular Weight: 746.88

Research Area: Metabolic Disease

Solubility: 10 mM in DMSO

Target: Apical Sodium-Dependent Bile Acid Transporter;Isotope-Labeled Compounds

• Artikelnummer: MEXHY-109120S1-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-109120S1-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK