Olopatadine-d6, CAS 1231979-85-3

Product Description: Olopatadine-d6 is the deuterium labeled Olopatadine[1]. Olopatadine is an orally active and selective histamine 1 (H1) receptor antagonist and a mast cell stabilizer. Olopatadine prevents immunologically stimulated pro-inflammatory mediator release from human conjunctival mast cells. Olopatadine can be used for researching allergic conjunctivitis[2][3].

Applications: COVID-19-immunoregulation

Formula: C21H17D6NO3

References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216./[2]Kam KW, et al. Topical Olopatadine in the Treatment of Allergic Conjunctivitis: A Systematic Review and Meta-analysis. Ocul Immunol Inflamm. 2017 Oct;25(5):663-677./[3]Leonardi A, et al. Olopatadine: a drug for allergic conjunctivitis targeting the mast cell. Expert Opin Pharmacother. 2010 Apr11(6):969-81.

CAS Number: 1231979-85-3

Molecular Weight: 343.45

Research Area: Inflammation/Immunology

Solubility: 10 mM in DMSO

Target: Endogenous Metabolite;Histamine Receptor

• Artikelnummer: MEXHY-W062109S-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-W062109S-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK