Oxolinic acid-d5, CAS 1189890-98-9

Product Description: Oxolinic acid-d5 is the deuterium labeled Oxolinic acid. Oxolinic acid is an antibiotic against both Gram-negative and Gram-positive bacteria. Oxolinic acid can be used for the research of acute and chronic urinary tract infections. Oxolinic acid is a DNA/RNA synthesis inhibitor. Oxolinic acid acts a dopamine uptake inhibitor and stimulants locomotor effect in mice[1][2][3].

Formula: C13H6D5NO5

References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. /[2]M J Kershaw, et al. The antibacterial and pharmacological activity of oxolinic acid (Prodoxol). J Antimicrob Chemother. 1975 Sep;1(3):311-5./[3]S H Manes, et al. Inhibition of RNA synthesis by oxolinic acid is unrelated to average DNA supercoiling. J Bacteriol. 1983 Jul; 155(1): 420-423./[4]J Garcia de Mateos-Verchere, et al. Behavioural and neurochemical evidence that the antimicrobial agent oxolinic acid is a dopamine uptake inhibitor. Eur Neuropsychopharmacol. 1998 Dec;8(4):255-9.

CAS Number: 1189890-98-9

Molecular Weight: 266.26

Compound Purity: 97.00

Research Area: Infection

Solubility: 10 mM in DMSO

Target: Antibiotic;Bacterial;DNA/RNA Synthesis;Isotope-Labeled Compounds

• Artikelnummer: MEXHY-B1002S-1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-B1002S-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK