Oxyphenbutazone-13C6

Product Description: Oxyphenbutazone-13C6 is the 13C6 labeled Oxyphenbutazone (HY-B1355A). Oxyphenbutazone is a phenylbutazone derivative, with anti-inflammatory effect. Oxyphenbutazone is a non-selective COX inhibitor. Oxyphenbutazone is the metabolite of Phenylbutazone (HY-B0230). Oxyphenbutazone selectively kills non-replicating Mycobaterium tuberculosis[1][2].

Applications: COVID-19-immunoregulation

Formula: C13 13C6H20N2O3

References: [1]Gold B, et al. Nonsteroidal anti-inflammatory drug sensitizes Mycobacterium tuberculosis to endogenous and exogenous antimicrobials. Proc Natl Acad Sci U S A. 2012 Oct 2;109(40):16004-11./[2]Saleem S, et al. Oxyphenbutazone promotes cytotoxicity in rats and Hep3B cellsvia suppression of PGE2 and deactivation of Wnt/β-catenin signaling pathway. Mol Cell Biochem. 2018 Jul;444(1-2):187-196./[3]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

Molecular Weight: 330.33

Research Area: Cancer; Infection; Inflammation/Immunology

Solubility: 10 mM in DMSO

Target: Bacterial;COX;Isotope-Labeled Compounds

• Artikelnummer: MEXHY-B1355AS1-1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-B1355AS1-1
• Green Labware: Nein
• Verpackungseinheit: 1mg
• Mengeneinheit: STK