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p,p'-DDE-d8, CAS 93952-19-3
p,p'-DDE-d8, CAS 93952-19-3
Artikelnummer
MEXHY-B1986S-0
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Hersteller
MedChemExpress
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Product Description: p,p'-DDE-d8 is the deuterium labeled p,p'-DDE[1]. p,p'-DDE (4,4'-DDE), a major metabolite of persistent dichlorodiphenyltrichloroethane (DDT), is a potent androgen receptor antagonist, with an IC50 of 5 μM and a Ki of 3.5 μM[2].
Formula: C14D8Cl4
References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216./[2]Kelce WR, et al. Persistent DDT metabolite p,p'-DDE is a potent androgen receptor antagonist. Nature. 1995;375(6532):581-585.
CAS Number: 93952-19-3
Molecular Weight: 326.07
Research Area: Endocrinology
Solubility: 10 mM in DMSO
Target: Androgen Receptor;Drug Metabolite
Formula: C14D8Cl4
References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216./[2]Kelce WR, et al. Persistent DDT metabolite p,p'-DDE is a potent androgen receptor antagonist. Nature. 1995;375(6532):581-585.
CAS Number: 93952-19-3
Molecular Weight: 326.07
Research Area: Endocrinology
Solubility: 10 mM in DMSO
Target: Androgen Receptor;Drug Metabolite
| Artikelnummer | MEXHY-B1986S-0 |
|---|---|
| Hersteller | MedChemExpress |
| Hersteller Artikelnummer | HY-B1986S-0 |
| Green Labware | Nein |
| Verpackungseinheit | Get quote |
| Mengeneinheit | STK |
| Produktinformation (PDF) | Download |
| MSDS (PDF) |
|
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