Perhexiline-d11 (maleate)

Product Description: Perhexiline-d11 (maleate) is the deuterium labeled Perhexiline maleate. Perhexiline maleate is a potent carnitine palmitoyltransferase 1 (CPT 1) inhibitor with IC50s of 77 and 148 μM for rat heart and liver CPT 1, respectively.

Formula: C23H28D11NO4

References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. /[2]Kennedy JA, et al. Inhibition of carnitine palmitoyltransferase-1 in rat heart and liver by Perhexiline and amiodarone. Biochem Pharmacol. 1996 Jul 26;52(2):273-80./[3]Vella S, et al. Perhexiline maleate enhances antitumor efficacy of cisplatin in neuroblastoma by inducing over-expression of NDM29 ncRNA. Sci Rep. 2015 Dec 17;5:18144.

Molecular Weight: 404.63

Research Area: Cancer; Cardiovascular Disease

Solubility: 10 mM in DMSO

Target: Isotope-Labeled Compounds;Mitochondrial Metabolism

• Artikelnummer: MEXHY-B1334AS-5
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-B1334AS-5
• Green Labware: Nein
• Verpackungseinheit: 5mg
• Mengeneinheit: STK