Propiconazole-d3 (nitrate), CAS 2699607-26-4

Product Description: Propiconazole-d3 (nitrate) is the deuterium labeled Propiconazole nitrate. Propiconazole is a broad-spectrum triazole fungicide that inhibits the conversion of lanosterol to ergosterol, leading to fungal cell membrane disruption. Propiconazole inhibits S. cerevisiae, but not rat liver, microsomal cytochrome P450 (IC50s=0.04 and >200 µM, respectively). Propiconazole inhibits the growth of T. deformans and R. stolonifer (ED50s=0.073 and 4.6 µg/mL, respectively). Propiconazole increases production of reactive oxygen species (ROS).

Formula: C15H15D3Cl2N4O5

References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

CAS Number: 2699607-26-4

Molecular Weight: 408.25

Research Area: Infection

Solubility: 10 mM in DMSO

Target: Fungal;Isotope-Labeled Compounds;Reactive Oxygen Species

• Artikelnummer: MEXHY-B0847S1-1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-B0847S1-1
• Green Labware: Nein
• Verpackungseinheit: 1mg
• Mengeneinheit: STK