Propiconazole-d7, CAS 1246818-14-3

Product Description: Propiconazole-d7 is the deuterium labeled Propiconazole. Propiconazole is a broad-spectrum triazole fungicide that inhibits the conversion of lanosterol to ergosterol, leading to fungal cell membrane disruption. Propiconazole inhibits S. cerevisiae, but not rat liver, microsomal cytochrome P450 (IC50s=0.04 and >200 µM, respectively). Propiconazole inhibits the growth of T. deformans and R. stolonifer (ED50s=0.073 and 4.6 µg/mL, respectively). Propiconazole increases production of reactive oxygen species (ROS)[1].

Applications: COVID-19-immunoregulation

Formula: C15H10D7Cl2N3O2

References: [1]Teng M, et al. Effect of Propiconazole on the Lipid Metabolism of Zebrafish Embryos ( Danio rerio). J Agric Food Chem. 2019;67(16):4623-4631./[2]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

CAS Number: 1246818-14-3

Molecular Weight: 349.26

Research Area: Infection

Solubility: 10 mM in DMSO

Target: Fungal;Isotope-Labeled Compounds;Reactive Oxygen Species

• Artikelnummer: MEXHY-B0847S-1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-B0847S-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK