(R)-3-O-Methyldopa-d3 (hydrochloride), CAS 2714485-35-3

Product Description: (R)-3-O-Methyldopa-d3 (hydrochloride) is a deuterium labeled (R)-3-O-Methyldopa, and (R)-3-O-Methyldopa is an R-enantiomer of 3-O-Methyldopa. 3-O-Methyldopa is a metabolite of L-DOPA which is formed by catechol-O-methyltransferase (COMT). 3-O-Methyldopa competitively inhibits the pharmacodynamics of L-DOPA and dopamine[1][2].

Applications: Neuroscience-Neuromodulation

Formula: C10H11D3ClNO4

References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216./[2]Asanuma M, Miyazaki I. 3-O-Methyldopa inhibits astrocyte-mediated dopaminergic neuroprotective effects of L-DOPA. BMC Neurosci. 2016 Jul 25;17(1):52.

CAS Number: 2714485-35-3

Molecular Weight: 250.69

Research Area: Neurological Disease

Solubility: 10 mM in DMSO

Target: Dopamine Receptor;Endogenous Metabolite

• Artikelnummer: MEXHY-W401531S1-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-W401531S1-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK