SAH-13C10, CAS 2687960-02-5

Product Description: SAH-13C10 is the 13C labeled SAH[1]. SAH (S-Adenosylhomocysteine) is an amino acid derivative and a modulartor in several metabolic pathways. It is an intermediate in the synthesis of cysteine and adenosine[2]. SAH is an inhibitor for METTL3-METTL14 heterodimer complex (METTL3-14) with an IC50 of 0.9 μM[3].

Applications: Metabolism-protein/nucleotide metabolism

Formula: C4 13C10H20N6O5S

References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216./[2]DE LA HABA G, et al. The enzymatic synthesis of S-adenosyl-L-homocysteine from adenosine and homocysteine. J Biol Chem. 1959 Mar;234(3):603-8./[3]Li F, et al. A Radioactivity-Based Assay for Screening Human m6A-RNA Methyltransferase, METTL3-METTL14 Complex, and Demethylase ALKBH5. Biomol Screen. 2016 Mar21(3):290-7.

CAS Number: 2687960-02-5

Molecular Weight: 394.34

Compound Purity: 99.90

Research Area: Metabolic Disease

Solubility: 10 mM in DMSO

Target: Endogenous Metabolite

• Artikelnummer: MEXHY-19528S2-100UG
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-19528S2-100UG
• Green Labware: Nein
• Verpackungseinheit: 100 μg
• Mengeneinheit: STK