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Sulindac sulfide-d3, CAS 250608-66-3
Sulindac sulfide-d3, CAS 250608-66-3
Artikelnummer
MEXHY-B1786S-1
Verpackungseinheit
1mg
Hersteller
MedChemExpress
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Product Description: Sulindac sulfide-d3 is deuterium labeled Sulindac sulfide. Sulindac sulfide is a noncompetitive γ-secretase inhibitor, with an IC50 of 20.2 μM for γ42-secretase activity.
Applications: Neuroscience-Neurodegeneration
Formula: C20H14D3FO2S
References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216./[2]Takahashi Y, et al. Sulindac sulfide is a noncompetitive gamma-secretase inhibitor that preferentially reduces Abeta 42 generation. J Biol Chem. 2003 May 16;278(20):18664-70.
CAS Number: 250608-66-3
Molecular Weight: 343.43
Research Area: Neurological Disease
Solubility: 10 mM in DMSO
Target: Isotope-Labeled Compounds;γ-secretase
Applications: Neuroscience-Neurodegeneration
Formula: C20H14D3FO2S
References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216./[2]Takahashi Y, et al. Sulindac sulfide is a noncompetitive gamma-secretase inhibitor that preferentially reduces Abeta 42 generation. J Biol Chem. 2003 May 16;278(20):18664-70.
CAS Number: 250608-66-3
Molecular Weight: 343.43
Research Area: Neurological Disease
Solubility: 10 mM in DMSO
Target: Isotope-Labeled Compounds;γ-secretase
| Artikelnummer | MEXHY-B1786S-1 |
|---|---|
| Hersteller | MedChemExpress |
| Hersteller Artikelnummer | HY-B1786S-1 |
| Green Labware | Nein |
| Verpackungseinheit | 1mg |
| Mengeneinheit | STK |
| Produktinformation (PDF) | Download |
| MSDS (PDF) |
|
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