Taurochenodeoxycholic acid-d5 (sodium)

Product Description: Taurochenodeoxycholic acid-d5 (sodium) is the deuterium labeled Taurochenodeoxycholic acid sodium. Taurochenodeoxycholic acid sodium salt (12-Deoxycholyltaurine sodium salt) is one of the main bioactive substances of animals' bile acid. Taurochenodeoxycholic acid induces apoptosis and shows obvious anti-inflammatory and immune regulation properties[1][2].

Formula: C26H39D5NNaO6S

References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. /[2]Wang X, et al. Taurochenodeoxycholic acid induces NR8383 cells apoptosis via PKC/JNK-dependent pathway. Eur J Pharmacol. 2016 Sep 5;786:109-15./[3]Zhou C, et al. The effects of taurochenodeoxycholic acid in preventing pulmonary fibrosis in mice. Pak J Pharm Sci. 2013 Jul;26(4):761-5./[4]Uchida A, et al. Taurochenodeoxycholic acid ameliorates and ursodeoxycholic acid exacerbates small intestinal inflammation. Am J Physiol. 1997 May;272(5 Pt 1):G1249-57./[5]Liu M, et al. Effects of taurochenodeoxycholic acid on adjuvant arthritis in rats. Int Immunopharmacol. 2011 Dec;11(12):2150-8.

Molecular Weight: 526.72

Compound Purity: 98.12

Research Area: Inflammation/Immunology

Solubility: DMSO : 100 mg/mL (ultrasonic;warming)

Target: Apoptosis;Endogenous Metabolite;Isotope-Labeled Compounds

• Artikelnummer: MEXHY-N1429S1-1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-N1429S1-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK