Product Description: Taurodeoxycholic acid-d5is the deuterium labeledTaurodeoxycholic acid(HY-B1899)[1]. Taurodeoxycholic acid, a bile acid, stabilizes the mitochondrial membrane, decreases free radical formation. Taurodeoxycholic acid inhibits apoptosis by blocking a calcium-mediated apoptotic pathway as well as caspase-12 activation. Taurodeoxycholic acid exhibits neuroprotective effect in 3-nitropropionic acid induced mouse model or genetic mouse model of Huntington's disease (HD)[2][3][4][5].
Formula: C26H40D5NO6S
References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.
Molecular Weight: 504.73
Research Area: Others
Solubility: 10 mM in DMSO
Target: Isotope-Labeled Compounds