Thymidine-d14, CAS 1134181-96-6

Product Description: Thymidine-d14 (DThyd-d14; NSC 21548-d14) is deuterium labeled Thymidine (HY-N1150). Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication.

Formula: C10D14N2O5

References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216./[2]Chen G, et al. Cell Synchronization by Double Thymidine Block. Bio Protoc. 2018 Sep 5;8(17)./[3]FIRKET H, et al. Autoradiographic visualization of synthesis of deoxyribonucleic acid in tissue culture with tritium-labelled thymidine. Nature. 1958 Jan 24;181(4604):274-5.FIRKET H, et al. Autoradiographic visualization of synthesis of deoxyribonucleic acid in tissue culture with tritium-labelled thymidine. Nature. 1958 Jan 24;181(4604):274-5./[4]Izeradjene K, et al. Inhibition of thymidine synthesis by folate analogues induces a Fas-Fas ligand-independentdeletion of superantigen-reactive peripheral T cells. Int Immunol. 2001 Jan;13(1):85-93.

CAS Number: 1134181-96-6

Molecular Weight: 256.31

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: DNA/RNA Synthesis;Endogenous Metabolite;Isotope-Labeled Compounds;Orthopoxvirus

• Artikelnummer: MEXHY-N1150S10-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-N1150S10-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK