Thymidine-d3, CAS 74848-84-3

Product Description: Thymidine-d3 is the deuterium labeled Thymidine. Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication[1][2][3].

Formula: C10H11D3N2O5

References: [1]FIRKET H, et al. Autoradiographic visualization of synthesis of deoxyribonucleic acid in tissue culture with tritium-labelled thymidine. Nature. 1958 Jan 24;181(4604):274-5.FIRKET H, et al. Autoradiographic visualization of synthesis of deoxyribonucleic acid in tissue culture with tritium-labelled thymidine. Nature. 1958 Jan 24;181(4604):274-5./[2]Izeradjene K, et al. Inhibition of thymidine synthesis by folate analogues induces a Fas-Fas ligand-independentdeletion of superantigen-reactive peripheral T cells. Int Immunol. 2001 Jan;13(1):85-93./[3]Chen G, et al. Cell Synchronization by Double Thymidine Block. Bio Protoc. 2018 Sep 5;8(17)./[4]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

CAS Number: 74848-84-3

Molecular Weight: 245.25

Research Area: Others

Solubility: 10 mM in DMSO

Target: DNA/RNA Synthesis;Endogenous Metabolite;Isotope-Labeled Compounds

• Artikelnummer: MEXHY-N1150S-1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-N1150S-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK