Trimipramine-d3 (maleate), CAS 1185245-93-5

Product Description: Trimipramine-d3 (maleate) is the deuterium labeled Trimipramine maleate. Trimipramine maleate is a 5-HT receptor antagonist, with pKis of 6.39, 8.10, 4.66 for 5-HT1C, 5-HT2 and 5-HT1A, respectively[1][2].

Applications: Neuroscience-Neuromodulation

Formula: C24H27D3N2O4

References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216./[2]Jenck F, et al. Evidence for a role of 5-HT1C receptors in the antiserotonergic properties of some antidepressant drugs. Eur J Pharmacol. 1993 Feb 9;231(2):223-9./[3]Juorio AV, et al. The effects of chronic trimipramine treatment on biogenic amine metabolism and on dopamine D2, 5-HT2 and tryptamine binding sites in rat brain. Gen Pharmacol. 1990;21(5):759-62.

CAS Number: 1185245-93-5

Molecular Weight: 413.52

Research Area: Neurological Disease

Solubility: 10 mM in DMSO

Target: 5-HT Receptor;Bacterial;Isotope-Labeled Compounds

• Artikelnummer: MEXHY-B1213S-1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-B1213S-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK