Veratric acid-d6, CAS 1162658-12-9

Product Description: Veratric acid-d6 is deuterium labeled Veratric acid. Veratric acid (3,4-Dimethoxybenzoic acid) is an orally active phenolic compound derived from vegetables and fruits, has antioxidant[1] and anti-inflammatory activities[3]. Veratric acid also acts as a protective agent against hypertension-associated cardiovascular remodelling[2]. Veratric acid reduces upregulated COX-2 expression, and levels of PGE2, IL-6 after UVB irradiation[3].

Applications: COVID-19-immunoregulation

Formula: C9H4D6O4

References: [1]Choi WS, et al. Veratric acid inhibits iNOS expression through the regulation of PI3K activation and histone acetylation in LPS-stimulated RAW264.7 cells. Int J Mol Med. 2015 Jan;35(1):202-10./[2]Saravanakumar M, et al. Oral administration of veratric acid, a constituent of vegetables and fruits, prevents cardiovascular remodelling in hypertensive rats: a functional evaluation. Br J Nutr. 2015 Nov 14;114(9):1385-94./[3]Shin SW, et al. Antagonist effects of veratric acid against UVB-induced cell damages. Molecules. 2013 May 10;18(5):5405-19./[4]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

CAS Number: 1162658-12-9

Molecular Weight: 188.21

Research Area: Inflammation/Immunology; Cardiovascular Disease

Solubility: 10 mM in DMSO

Target: COX;Isotope-Labeled Compounds;Reactive Oxygen Species

• Artikelnummer: MEXHY-N2007S-1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-N2007S-1
• Green Labware: Nein
• Verpackungseinheit: 1mg
• Mengeneinheit: STK