Zileuton-13C2,15N

Product Description: Zileuton-13C2,15N is 15N and 13C labeled Zileuton (HY-14164). Zileuton is a potent and selective inhibitor of 5-lipoxygenase with antiasthmatic properties.

Applications: COVID-19-immunoregulation

Formula: C9 13C2H8N 15NO2S

References: [1]Gounaris E, et al. Zileuton, 5-lipoxygenase inhibitor, acts as a chemopreventive agent in intestinal polyposis, by modulating polyp and systemic inflammation. PLoS One. 2015 Mar 6;10(3):e0121402/[2]Abueid L, et al. Inhibition of 5-lipoxygenase by zileuton in a rat model of myocardial infarction. Anatol J Cardiol. 2016 Nov 10/[3]Kuvibidila S, et al. Hydroxyurea and Zileuton Differentially Modulate Cell Proliferation and Interleukin-2 Secretion by Murine Spleen Cells: Possible Implication on the Immune Function and Risk of Pain Crisis in Patients with Sickle Cell Disease. Ochsner/[4]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

Molecular Weight: 235.24

Research Area: Cancer; Inflammation/Immunology

Solubility: 10 mM in DMSO

Target: Ferroptosis;Isotope-Labeled Compounds;Lipoxygenase

• Artikelnummer: MEXHY-14164S1-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-14164S1-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK