AZD 5462, CAS 2787501-83-9

Formulation: A solid

Formal Name: cis-4-[2-fluoro-4-methoxy-5-[[[(1S,2R,3S,4R)-3-[[[(1-methylcyclobutyl)methyl]amino]carbonyl]bicyclo[2.2.1]hept-2-yl]amino]carbonyl]phenoxy]-1-methyl-cyclohexanecarboxylic acid

Purity: ≥98%

Formula Markup: C30H41FN2O6

Formula Weight: 544,7

Shelf life (days): 1460

CAS Number: 2787501-83-9

Notes: AZD 5462 is an agonist of relaxin family peptide receptor 1 (RXFP1).{67792} It induces cAMP mobilization in HEK293 cells expressing the human RXFP1 (EC50 = 15.85 nM). AZD 5462 increases heart rate and mean arterial blood pressure (MABP) in rats. It increases left ventricular ejection fraction (LVEF) in a cynomolgus monkey model of heart failure induced by a high-fat diet and age when administered at doses of 1 or 10 mg/kg per day.

• Artikelnummer: CAY40956-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 40956-5
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK