Bepotastine, CAS 125602-71-3

Formulation: A solid

Formal Name: 4-[(S)-(4-chlorophenyl)-2-pyridinylmethoxy]-1-piperidinebutanoic acid

Purity: ≥98%

Formula Markup: C21H25ClN2O3

Formula Weight: 388,9

Shelf life (days): 1460

CAS Number: 125602-71-3

Notes: Bepotastine is an antagonist of the histamine H1 receptor that is selective over H3, α1-, α2-, and β-adrenergic, dopamine D2long, serotonin 5-HT2, muscarinic acetylcholine, and benzodiazepine receptors.{40405} It reduces dye leakage from the nasal passages of rats acutely sensitized to an antigen (ED50 = 0.03 mg/kg) and inhibits histamine-induced bronchoconstriction in the anesthetized dog (ED50 = 3.2 µg/kg).{40408,40407} Bepotastine prevents conjunctival vascular hyperpermeability in a guinea pig model of conjunctivitis in a dose-dependent manner.{40406} Formulations containing bepotastine have been used in the treatment of itching associated with allergic conjunctivitis.

• Artikelnummer: CAY39932-25
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 39932-25
• Verpackungseinheit: 25 mg
• Mengeneinheit: STK