Cucurbitacin IIa, CAS 58546-34-2

Formulation: A solid

Formal Name: (2β,3α,9β,10α,16α)-25-(acetyloxy)-2,3,16,20-tetrahydroxy-9-methyl-19-norlanost-5-ene-11,22-dione

Purity: ≥98%

Formula Markup: C32H50O8

Formula Weight: 562,7

Shelf life (days): 1460

CAS Number: 58546-34-2

Notes: Cucurbitacin IIa is a triterpenoid that has been found in H. amabilis and has diverse biological activities. {68509,68510,68511} It decreases the proliferation of (IC50 = 370 nM), and induces cell cycle arrest at the G2/M phase and apoptosis in, HT-29 colorectal adenocarcinoma cells when used at a concentration of 1 µM.{68509} Cucurbitacin IIa (2.5 µM) induces cell cycle arrest at the G0/G1 phase in LPS-stimulated, but not unstimulated, RAW 264.7 macrophages.{68510} In vivo, cucurbitacin IIa (5 mg/kg) decreases immobility time in the forced swim test and the tail suspension test in a mouse model of intermittent unpredictable stress.{68511}

• Artikelnummer: CAY37371-1
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 37371-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK