Azido-Thalidomide, CAS 2098488-36-7

Formulation: A crystalline solid

Formal Name: N-(4-azidobutyl)-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-acetamide

Purity: ≥95%

Formula Markup: C19H20N6O6

Formula Weight: 428,4

Shelf life (days): 1460

CAS Number: 2098488-36-7

Notes: Azido-thalidomide is a building block in the synthesis of proteolysis-targeting chimera (PROTAC) technologies.{46112} It contains thalidomide, which is a ligand for the E3 ubiquitin ligase cereblon, and can be conjugated to alkynylated ligands for target proteins via click chemistry. Azido-thalidomide has been used in the synthesis of a SirReal-based PROTAC for the degradation of sirtuin 2 (Sirt2) in cells.

• Artikelnummer: CAY26146-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 26146-5
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK
• Methode: Click Chemistry