COX-2 (ovine) Electrophoresis Standard

Formulation: 5 µg of purified COX-2

Purity: ≥95%

Shelf life (days): 365

Notes: Cyclooxygenase 2 (COX-2) is a bifunctional enzyme that exhibits both COX and peroxidase activities and catalyzes the first step in the biosynthesis of prostaglandins, thromboxanes, and prostacyclins.{500,501} The COX component converts arachidonic acid to the hydroperoxy endoperoxide prostaglandin G2 (PGG2; Item No. 17010), and the peroxidase component reduces the endoperoxide to the corresponding alcohol PGH2 (Item No. 17020). COX2 expression is induced by a variety of stimuli, including phorbol esters, LPS, and cytokines and is responsible for the biosynthesis of PGs under acute inflammatory conditions.{54420,14766} Thus, COX-2 has been the focus of attention for nonsteroidal anti-inflammatory drug (NSAID) development. This product is intended to be used as a standard for Western blot (WB) and electrophoresis. This enzyme has been carefully purified to exclude all unrelated proteins and may not be catalytically active.

• Artikelnummer: CAY360120
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 360120-1
• Green Labware: Nein
• Verpackungseinheit: 1 Piece
• Mengeneinheit: STK
• Methode: Western Blotting, Electrophoresis