CPT2, CAS 1670277-66-3

Product Description: CPT2 (Carnitine palmitoyltransferase 2), an enzyme that participates in fatty acid oxidation, also is a colorectal cancer (CRC) prognostic biomarker. CPT2 overexpression can activate p-p53 to increase p53 expression, thereby inhibiting tumor proliferation and promoting apoptosis. CPT2 deficiency results in the most common inherited disorder of long-chain fatty acid oxidation affecting skeletal muscle. Downregulation of CPT2 is also highly correlated with the progression of various cancers and has potential for cancer research[1][2].

Applications: Metabolism-sugar/lipid metabolism

Formula: N/A

References: [1]Liu F, et al. Downregulation of CPT2 promotes proliferation and inhibits apoptosis through p53 pathway in colorectal cancer. Cell Signal. 2022 Apr;92:110267. /[2]Joshi PR, et al. Muscle Carnitine Palmitoyltransferase II (CPT II) Deficiency: A Conceptual Approach. Molecules. 2020 Apr 13;25(8):1784.

CAS Number: 1670277-66-3

Molecular Weight: N/A

Research Area: Cancer; Metabolic Disease

Solubility: 10 mM in DMSO

Target: Apoptosis;MDM-2/p53

• Artikelnummer: MEXHY-108433-50UG
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-108433-50UG
• Green Labware: Nein
• Verpackungseinheit: 50 μg
• Mengeneinheit: STK